The Iowa state patrol is investigating an early morning fatal accident in Dallas County.
The patrol says around midnight 24-year-old Megan Wakeham of West Des Moines was driving eastbound in the westbound lanes of Interstate 80.
Wakeham hit a Pontiac Firebird head-on. An SUV then rear ended the Firebird.
Wakeham, the driver travelling the wrong way, was pronounced dead on the scene.
The other two drivers were taken to metro hospitals for their injuries.
Authorities shutdown the interstate, near Earlham for several hours overnight to investigate.